Modeling presynapse-astrocyte interactions
نویسندگان
چکیده
منابع مشابه
Comment on recent modeling studies of astrocyte-neuron metabolic interactions.
Recent years have seen a surge in mathematical modeling of the various aspects of neuron-astrocyte interactions, and the field of brain energy metabolism is no exception in that regard. Despite the advent of biophysical models in the field, the long-lasting debate on the role of lactate in brain energy metabolism is still unresolved. Quite the contrary, it has been ported to the world of differ...
متن کاملEndothelial Cell- Astrocyte Interactions
Recent advances in cell biology open the way for studying aspects of blood-brain bamer (BBB) formation and function that have puzzled investigators since Ehrlich and Goldmann first described the barrier. Although the endothelial cells in the microvessels of all tissues appear to arise from common mesodermal precursors, considerable organ-to-organ variability exists in their ultrastructure and p...
متن کاملMetabolic Aspects of Neuron-Oligodendrocyte-Astrocyte Interactions
Whereas astrocytes have been in the limelight of scientific interest in brain energy metabolism for a while, oligodendrocytes are still waiting for a place on the metabolic stage. We propose to term the interaction of oligodendrocytes with astrocytes and neurons: NOA (neuron-oligodendrocyte-astrocyte) interactions. One of the reasons to find out more about metabolic interactions between oligode...
متن کاملModeling Neuron-Astrocyte Metabolic Interactions: From Hodgkin-Huxley to the BOLD Signal
In order to study how neurons and astrocytes modulate imaging signals like the BOLD signal, we developed a mathematical model of the metabolic neuron-astrocyte interactions. Our model is based on recent work by Aubert and Costalat connecting the principal metabolic pathways to the cerebral blood flow [2]. The novelty is that our model is the first to bridge the gap between these approaches and ...
متن کاملCellular and molecular mechanisms underlying presynapse formation
Synapse formation is a highly regulated process that requires the coordination of many cell biological events. Decades of research have identified a long list of molecular components involved in assembling a functioning synapse. Yet how the various steps, from transporting synaptic components to adhering synaptic partners and assembling the synaptic structure, are regulated and precisely execut...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2015
ISSN: 1662-453X
DOI: 10.3389/conf.fnins.2015.91.00036